Transcranial Focused Ultrasound (tFUS) and Transcranial Unfocused Ultrasound (tUS) Neuromodulation: From Theoretical Principles to Stimulation Practices
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چکیده
منابع مشابه
Transcranial focused ultrasound stimulation of human primary visual cortex
Transcranial focused ultrasound (FUS) is making progress as a new non-invasive mode of regional brain stimulation. Current evidence of FUS-mediated neurostimulation for humans has been limited to the observation of subjective sensory manifestations and electrophysiological responses, thus warranting the identification of stimulated brain regions. Here, we report FUS sonication of the primary vi...
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BACKGROUND/OBJECTIVE Transcranial ultrasound (TUS) can modulate brain function. To assess possible TUS modulation of mental states, we investigated effects on subjective reports of pain and mood of sub-thermal TUS versus placebo applied to frontal scalp and brain of chronic pain patient volunteers. METHODS With IRB approval and informed consent, subjects with chronic pain completed two visual...
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Targeted, noninvasive neuromodulation of the brain of an otherwise awake subject could revolutionize both basic and clinical neuroscience. Toward this goal, we have developed nanoparticles that allow noninvasive uncaging of a neuromodulatory drug, in this case the small molecule anesthetic propofol, upon the application of focused ultrasound. These nanoparticles are composed of biodegradable an...
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Background: Recently, ultrasonic neuromodulation research has been an important and interesting issue. Ultrasonic neuromodulation is possible by the use of low-intensity transcranial focused ultrasound (tFUS) to stimulate or inhibit the neural structures. The primary capability of this method is the improvement in the treatment progress of certain neurological and psychiatric disorders noninvas...
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Analysis of Transcranial Focused Ultrasound Beam Profile Sensitivity for Neuromodulation of the Human Brain Jerel K. Mueller, Wynn Legon, and William J. Tyler* 1 School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 2 Dept. of Physical Medicine and Rehabilitation, University of Minnesota, Minneapolis, MN 3 School of Biological and Health Systems Engineering, Arizona State...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2019
ISSN: 1664-2295
DOI: 10.3389/fneur.2019.00549